Press releases

Pharmacy

Promising results for new Alzheimer therapy

13 February, 2015 - Karolinska Institutet

[PRESS RELEASE 02/13/2015] Scientists at Karolinska Institutet have evaluated a new Alzheimer’s therapy in which the patients receive an implant that stimulates the growth of a certain type of nerve cell. The results, which are published in the scientific journal ‘Alzheimer’s & Dementia’, suggest that the introduction of a nerve growth factor can prevent neuronal degradation in Alzheimer’s patients.

New therapeutic principle for Parkinsonian dyskinesia shows clinical effect

10 February, 2015 - Karolinska Institutet

[PRESS RELEASE 02/10/2015] Involuntary dyskinetic movements induced by treatment with levodopa (L-dopa) are a common problem for people with Parkinson’s disease. Now, however, researchers at Karolinska Institutet and Lund University in Sweden seem to be close to a novel therapy to this distressing side effect. A treatment study published in the scientific periodical Brain shows that a drug that stimulates certain serotonin receptors in the brain counteracts the dyskinesia causing effects of L-dopa.

Gut microbiota influences blood-brain barrier permeability

20 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/20/2014] A new study in mice, conducted by researchers at Sweden’s Karolinska Institutet together with colleagues in Singapore and the United States, shows that our natural gut-residing microbes can influence the integrity of the blood-brain barrier, which protects the brain from harmful substances in the blood. According to the authors, the findings provide experimental evidence that our indigenous microbes contribute to the mechanism that closes the blood-brain barrier before birth. The results also support previous observations that gut microbiota can impact brain development and function.

Young vessels rejuvenate aged insulin-producing beta cells

18 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/18/2014] A recent study published in the journal PNAS shows that young capillary vessels rejuvenate aged pancreatic islets. The finding challenges prevailing views on the causes of age-dependent impaired glucose balance regulation, a condition that often develops into diabetes type 2. The international research team behind the study now suggests that targeting inflammation and fibrosis in the small blood vessels of the pancreatic islets may offer a new way of treatment for age-dependent dysregulation of blood glucose levels.

Beta blockers could benefit patients with HFPEF

16 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/16/2014] A novel registry study from Karolinska Institutet in Sweden suggests that beta blockers may benefit also patients suffering from a relatively unknown form of heart failure called HFPEF, which today lacks well-established treatment. HFPEF involves an impaired ability of the heart to fill with blood, and affects nearly 2 per cent of the population. These new findings are being published in the scientific periodical JAMA.

Molecular time signalling controls stem cells during brain’s development

13 November, 2014 - Karolinska Institutet

[PRESS RELEASE 11/13/2014] Researchers at Karolinska Institutet in Sweden have succeeded in explaining how stem cells in the brain change to allow one type of stem cell to produce different cell types at different stages. In a study being published in the journal Neuron, researchers show that the signal molecule TGF-beta acts as a time signal that regulates the nerve stem cells’ potential at different stages of the brain’s development – knowledge that may be significant for future pharmaceutical development.

Very low concentrations of heavy metals and antibiotics in the environment contribute to resistance problems

8 October, 2014 - Uppsala universitet

New research at Uppsala University shows that plasmids containing genes that confer resistance to antibiotics can be enriched by very low concentrations of antibiotics and heavy metals. These results strengthen the suspicion that the antibiotic residues and heavy metals (such as arsenic, silver and copper) that are spread in the environment are contributing to the problems of resistance.

Mechanism behind age-dependent diabetes discovered

17 September, 2014 - Karolinska Institutet

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden. The finding, which is published in the journal Diabetes, provides a new molecular mechanism underlying age-related impairment of insulin-producing cells and diabetes.

Karolinska Institutet is now starting up the first MOOC in Sweden

9 September, 2014 - Karolinska Institutet

Today, Sweden’s medical university, Karolinska Institutet, becomes the first university in the country to offer MOOCs (massive open online courses). This means that the university will be enriched this autumn by more than 70,000 new course participants from all over the world who will benefit from the top expertise of its teaching staff on a daily basis.

From a single cell to a full nervous system

25 August, 2014 - Karolinska Institutet

Research has long been occupied by one of the great mysteries in life: how one single cell can form a human brain. In the last few years, thanks to new methods and technology, our knowledge of how the nervous system is developed has grown significantly. During a conference at Karolinska Institutet, we will get to know where the current frontiers are found.