Great variations in levels of blood sugar are being associated more and more with the risk of old-age diabetes, obesity, and cardiovascular diseases. These findings can therefore provide valuable information for tailoring a new generation of whole-grain products with low GI that can counteract these so-called lifestyle diseases. They may also have a beneficial effect on short-term memory and mental acuity.
“It is known that a carbohydrate-rich breakfast with low GI can moderate increases in blood sugar after lunch. But my results show that low GI in combination with the right amount of so-called indigestible carbohydrates, that is, dietary fiber and resistant starch, can keep the blood-sugar level low for up to ten hours, which means until after dinner,” says Anne Nilsson, a doctoral student at the Unit for Applied Nutrition and Food Chemistry and author of the dissertation.
Experiments also showed that the blood sugar increase following breakfast can be moderated in a similar way by eating the right grain products the night before.
Barley evinced clearly the best results of the four types of grain. In her test, Anne used boiled grains and whole grains in bread. But when the grain was ground into porridge, the effect was weakened, since key structures were then destroyed, which had a negative effect on both GI and the content of resistant starch. On the other hand, splitting the grain worked fine.
The studies also revealed that the right grain can have a favorable impact on the metabolic syndrome, which is a catch-all name for a condition involving severe risk of diabetes and cardiovascular diseases. The diagnosis includes heightened levels of blood sugar and insulin, raised blood fats, high blood pressure, and abdominal fat. When you eat indigestible carbohydrates, they ferment in the large intestine. This bacterial process proved to have a beneficial effect on a number of risk factors for metabolic syndrome, such as markers for inflammation and level of insulin efficiency. The process also produced a greater sense of satiety.
Anne Nilsson also studied the connection between mental acuity and blood sugar levels after meals. Trial subjects were given experimental breakfasts with low and high GI, respectively, and afterwards they were asked to perform mental acuity tests. It turned out that subjects who had eaten low GI breakfasts could concentrate better and had a better working memory (a type of short-term memory) than the other group. These experiments also showed that healthy individuals with low glucose tolerance, that is with high rises in blood sugar than average following a meal, generally performed less well.
“The findings indicate that people with great fluctuations in their levels of blood sugar run a greater risk of having a generally lower cognitive ability,” says Anne Nilsson.
Anne Nilsson will publicly defend her dissertation on September 7 at 9:15 a.m. at the Department of Chemistry, Lecture Hall B, Getingevägen 60. The public is welcome. Read the abstract at http://theses.lub.lu.se/postgrad/search.tkl?field_query1=pubid&query1=tec_1220&recordformat=display
Glycemic Index (GI) is a measure of how rapidly the level of blood sugar rises after ingestion of food containing carbohydrates. The rapidity of the increase depends on how long it takes for the body to break down the carbohydrates in the intestines to glucose and then absorb the glucose into the blood. When you eat products with a low GI, the blood sugar level rises slowly and the insulin increase is lower. Foods with low GI offer several health advantages.
Indigestible carbohydrates are carbohydrates that are not broken down in the small intestine but rather reach the large intestine, where they provide nourishment for the intestinal bacteria. This triggers a fermentation process that produces various components, such as short-chain fatty acids. Anne Nilsson’s studies show that components produced in the process of fermentation can enter the blood and favorably affect the regulation of blood sugar and the feeling of satiety, and they can help alleviate inflammatory conditions in the body, which in turn can entail a reduced risk of diabetes and cardiovascular diseases.