“Modern research techniques, new communication technology, advanced and increasingly high throughput laboratory methods, as well as developments in genetics have created unique conditions for studying the origin of disease,” says Nancy Pedersen, professor of genetic epidemiology at Karolinska Institutet and director of the LifeGene project. “Thanks to various health registries and biobanks, the Nordic countries are better equipped than any other to lead the development of disease prevention and improve public health. This requires new and visionary efforts. LifeGene is one such effort.”
LifeGene provides unique opportunities for understanding the complex interaction between environment, lifestyle factors and heredity in the origin of disease. The data made available through LifeGene is accessible to scientists at universities around the world. The LifeGene project is a collaboration between all medical faculties in Sweden, and is hosted by Karolinska Institutet. The project will gather information on the health and lifestyles of 500,000 Swedes, as well as blood and urine samples for later analysis. The objective is to improve diagnostics, treatments and preventative recommendations. Participation in LifeGene is voluntary and participants are monitored for many years with regular health checks and lifestyle questionnaires.
“LifeGene provides unique opportunities for helping us better understand why some individuals are more vulnerable to certain diseases than others, and, for example, the reasons why people can respond differently to medication,” says Professor Pedersen. She continues: “Epidemiologists, clinical and non-clinical researchers in biomedicine can all benefit from LifeGene. Research done on the biological material in the LifeGene biobank can lead to discoveries on the course of diseases at a molecular level.”
Because parents may include their children in the project from birth, LifeGene can give vital information on diseases that occur early in life. This makes it unique in the world, as other health-based population studies mainly comprise individuals over the age of 45, and are focused on diseases that normally appear around middle age.
By combining decades of extensive and regular biosampling at dedicated test centres with web-based health surveys, LifeGene will create databases of biological and lifestyle data from half a million individuals aged 0 to 45. The information thus generated will create a rich platform for a myriad of research projects and provide researchers with opportunities to explore the factors that can impact health later in life, especially from infancy.
LifeGene is a unique project to better understand how our genes, environment and lifestyles affect our health. For more information, see www.lifegene.se.
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For further information, contact:
Professor Nancy Pedersen
Mobile: +46-(0)70 664 5528
Dr Jens G Mattsson, CEO LifeGene
Mobile: +46 (0)70 970 1710
Helen Larsson, Communications Manager, LifeGene
Mobile: +46(0)76 245 7533
Sabina Bossi, Press Officer, Karolinska Institutet
Mobile: +46(0)70 614 6066